468例甲真菌病临床类型及病原菌分析

Clinical types and pathogenic fungus analysis of 468 onychomycosis cases

目的探讨本地区甲真菌病的菌种构成、临床分型和各年龄段发病情况。方法对2010年1月至2013年12月来平湖市中医院皮肤科就诊的468例甲屑培养阳性病例病原菌进行回顾性统计分析。结果甲真菌病以皮肤癣菌为主,占58.76%;酵母菌次之,占30.13%;霉菌第三,占11.11%。临床分型远端甲下型（DLSO）、全甲营养不良型（TDO）、近端甲下型（PSO）和浅表白色型（SWO）分别为50.64%、25.21%、16.03%和8.12%。发病年龄以36-50岁为主,20-35岁次之。结论甲真菌病病原菌以皮肤癣菌为主,临床分型以DLSO型为主,年龄分布以20-50岁为主。

Objective To analyze the pathogenic fungus distribution,clinical types and onset of onyehomyeosis in people of all ages in Pinghu region. Methods A retrospective analysis was conducted on the fungal culture results of 468 onychomycosis patients from Jan. 2010 to Dec. 2013. Results The most frequently isolated fungus was dermatophytes（ 58. 76%）,followed by yeasts（ 30. 13%） and saprophyticmolds（ 11. 11%）. DLSO（ 50. 64%）was the most frequently found clinical type,followed by TDO（ 25. 21%）,PSO（ 16. 03%） and SWO（ 8. 12%）.The most common age of onset fell in 36 to 50 years old,followed by 20 to 35 years old. Conclusion The most frequently isolated fungus in onychomycosis is dermatophytes; DLSO is the most frequently found clinical type; the age of 20 to 50 years old is the primary onset age.