黄瓜香醇提取液治疗细菌性阴道炎疗效观察

Effect of Huangguaxiang on bacterial vaginosis

目的观察黄瓜香醇提取液治疗细菌性阴道炎的疗效。方法用黄瓜香醇提取液治疗细菌性阴道炎,治疗前后分别测阴道分泌物p H、做线索细胞和胺试验检查,进行总有效率评定。结果黄瓜香醇提取液治疗后所有患者临床症状均明显减轻,治疗前后自身比较差异有统计学意义(P<0.01);83%以上的患者呈现线索细胞转(-)、胺试验转(-),超过一半的患者阴道分泌物p H低于4.5;临床治疗总有效率为76.66%。结论黄瓜香醇提取液能够治疗细菌性阴道炎,有可能成为治疗细菌性阴道炎的新药。

Objective To observe the effect of Huangguaxiang（ Matteuccia struthiopteris） in treatment of bacterial vaginosis. Methods Patients with bacterial vaginosis were administered Huangguaxiang extract intravaginally.Clinical symptoms and p H of vaginal discharges were observed,and clue cells and ammonia tests were performed using vaginal swab specimens before and after the treatment. Total efficacy was evaluated. Results The clinical symptoms were reduced in most of the patients after the treatment. There were significant differences in each patient between pre- and post-treatment（ P 0. 01）. The p H values of vaginal discharge specimens were lower than 4. 5 in over 50% of the patients. More than 83% of the samples were negative in the clue cells and ammonia tests. The total efficacy rates were 76. 66%. There were no significant differences between the two groups（ P 0. 05）. Conclusion Intra-vaginal administration of Huangguaxiang extract is as effective as Metronidazole and may be a new method for the treatment of bacterial vaginits.