中药有效成分及单体抗菌作用机制的研究进展

The antibacterial effects of herb monomers: research advances

目前全球面临耐药形势严峻的挑战,更迫切寻找新的结构和新的作用机制的药物。许多中药具有抑菌或潜在抗感染作用,本研究收集整理国内外相关文献,对中药有效成分及单体抗菌的生物活性及机制方面作一综述,为中药单体在抗感染应用提供理论依据,加快中药单体抗感染的开发利用。

The whole world is facing a severe challenge of drug resistance nowadays with more urgent need to find new structures and drugs with new mechanisms of action. Many traditional Chinese medicines have antibacterial or potential anti-inflammatory effects. This paper reviewed the relevant literatures on the biological activity and mechanisms of active ingredients and antibacterial monomers of traditional Chinese medicines,so as to provide a theoretical basis for the application of these anti-infective monomers,and promote the development of anti-infective herbal monomers