摘要
目的探讨丙戊酸镁联合艾司西酞普兰治疗抑郁症的临床疗效和安全性。方法将80例抑郁症患者随机分为两组,两组均口服艾司西酞普兰治疗,研究组联合丙戊酸镁,观察6周。治疗前后采用汉密尔顿抑郁量表评定临床疗效,副反应量表评定不良反应。结果治疗6周后,研究组显效率为90.00%,对照组为67.50%,研究组显著高于对照组(P<0.05);治疗后两组的不良反应轻微,发生率比较差异无显著性(P>0.05)。结论丙戊酸镁联合艾司西酞普兰治疗抑郁症疗效显著,起效快,安全性高,依从性好,优于单用艾司西酞普兰治疗。
Objective To explorer the efficacy and safety of magnesium valproate combined with escitalopram in depression patient. Methods go cases of depression patients were randomly assigned to two groups took orally escitalopram and research group was plus magnesium valproate for 6 weeks. Efficacies were assessed with the HAMD before and after treatment and adverse reactions with the TESS. Results At the end of the 6 weeks obvious effective rate was significantly higher in research group than control group （ 90.00%vs.67.51）%, P〈0.05 ） ; after treatment adverse reactions of both groups were mild, their incidences had no significant group differences （ P〉0.05 ） . Conclusion Magilesium valproate combined with escitalopram has an evident effect safety and better compliance, takes eftect more rapidly compared with single escitalopram in depression patient.
出处
《中国卫生标准管理》
2015年第5期14-16,共3页
China Health Standard Management
