埃索美拉唑在糜烂性食管炎治疗中的应用研究

Study on Esomeprazole Application in the Treatment of Erosive Esophagitis

目的：探究糜烂性食管炎患者采用埃索美拉唑的治疗方法和效果。方法选取2013年1月～2014年7月收治的32例糜烂性食管炎患者进行治疗，随机分组，实验组19例选择埃索美拉唑，对照组13例患者选择奥美拉唑的治疗，观察患者身体的恢复情况。结果实验组有效率为94.74%，对照组有效率为76.92%。差异显著，有统计学意义（P〈0.05）。结论糜烂性食管炎患者采用埃索美拉唑的治疗，可在短时间内治愈身体病症，起效快，疗效显著，没有严重的不良反应情况。

Objective To explore esomeprazole medication treatment approach and its effect to patients with erosive esophagitis.MethodsChoose 32 patients with erosive esophagitis who are treated in hospital from January 2013 to July 2014 and separate them into two groups at random; 19 patients in study group are given esomeprazole medication treatment,while 13 patients in control group are given omeprazole medication treatment; and then compare treatment effects between two groups.Results Treatment efficacy in study group is up to 94.74%; while treatment efficacy in control group is 76.92%; there is a treatment differential between two groups,and such a differential has statistic value（P〈0.05）.Conclusion Esomeprazole medication is of efficacy in treatment of patients with erosive esophagitis; it is conducive to improving patients’ ilness symptom rapidly and effectively without any side effect; thus,it is quite worthwhile to be promoted widespread.