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骶骨脊索瘤的治疗概况 被引量:3

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摘要 目的:了解骶骨脊索瘤的治疗概况。方法:查阅近年国内外关于骶骨脊索瘤的治疗方面相关文献,综述骶骨脊索瘤的手术治疗、放疗与化疗、分子生物学治疗方面新方法、新技术、新思路。结果:手术仍是骶骨脊索瘤治疗有效方法,术前靶血管栓塞技术等的使用可使术野更清晰、手术更便利;术前使白蛋白>3.0 g·L-1、手术时间<6.0 h、手术由单一团队完成可降低术后切口并发症发生率;包括质子和碳离子的粒子束放疗及术中间隔放疗安全有效;骶骨脊索瘤的分子生物学特点为其治疗提供了新靶点及治疗途径。结论:肿瘤广泛切除术仍然安全有效且更加成熟;粒子束放疗及术中间隔放疗有望成为替代单纯手术治疗的新方法;骶骨脊索瘤的分子生物学特点为其治疗打开了新思路。
出处 《东南大学学报(医学版)》 CAS 北大核心 2015年第1期127-131,共5页 Journal of Southeast University(Medical Science Edition)
基金 国家自然科学基金资助项目(81272035)
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参考文献38

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二级参考文献87

共引文献34

同被引文献23

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