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低钙腹透液和碳酸钙治疗腹透患者皮肤瘙痒疗效观察 被引量:8

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摘要 目的:评价低钙腹透液和含钙的磷结合剂(碳酸钙)治疗对腹膜透析患者甲状旁腺激素及皮肤瘙痒发病率的影响。探讨纠正腹膜透析患者继发性骨病治疗新方法。方法:60例腹膜透析合并皮肤瘙痒患者按照随机原则分为治疗组及对照组,治疗组使用低钙腹透液(钙浓度1.25 mmol/L)和碳酸钙治疗,对照组使用普通钙浓度腹透液(钙浓度1.75 mmol/L)治疗,不使用磷结合剂。治疗时间6个月,在实验前和结束后分别测定患者甲状旁腺激素及C反应蛋白激素水平、皮肤瘙痒发病率,评价治疗效果。结果:使用低钙腹透液和碳酸钙治疗6月后,甲状旁腺激素与治疗前后浓度变化差异有统计学意义(P<0.05),超敏C反应蛋白浓度变化差异无统计学意义(P>0.05)。治疗前后皮肤瘙痒发病率差异有统计学意义(P<0.05),对照组患者上述三种指标变化均差异无统计学意义。结论:低钙腹透液和碳酸钙治疗6月后可以降低甲状旁腺激素浓度水平,可以缓解皮肤瘙痒发病率。
作者 郑磊
出处 《中国中西医结合肾病杂志》 2015年第1期53-54,共2页 Chinese Journal of Integrated Traditional and Western Nephrology
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参考文献6

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