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循环肿瘤细胞在肺癌诊断及预后中的应用 被引量:4

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摘要 肺癌的传统诊断主要依赖于常规病理组织学检查和影像学手段,难以实时监测肿瘤的转移和复发。循环肿瘤细胞(CTCs)作为一种代表原发性肿瘤的"液态活检标本",有助于实时、无创性地进行组织学鉴定。CTCs的数目与肿瘤发展状况呈正相关。因此,CTCs检测可能成为肺癌早期诊断、监测肿瘤复发与转移的一种重要手段。同时,CTCs也可用于评估肺癌的疗效和预后。CTCs在血液中含量极少,为了使检测的灵敏性达到临床可接受的水平,需先富集再检测,几种检测方法各有利弊,在临床上可以将其联合使用,以期计数结果更为准确。
出处 《诊断病理学杂志》 CSCD 2015年第2期117-121,共5页 Chinese Journal of Diagnostic Pathology
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