不完全川崎病67例分析

Clinical Analysis on 67 Caese with Incomplete Kawasaki

目的:总结不完全川崎病(KD)的临床特点。方法:分析67例不完全KD患儿(不完全KD组)和同期81例典型KD患儿(典型KD组)的主要临床表现、其他系统症状、实验室指标、免疫球蛋白(IVIG)治疗无反应例数及冠状动脉受损(CAL)发生率。结果:不完全KD组患儿除卡疤红斑及肛周潮红脱屑发生率高于典型KD组(P<0.05)外,呼吸、消化和神经系统症状两组比较,差异无统计学意义(P>0.05);两组患儿的实验室指标异常比例以及IVIG治疗无反应比例比较,差异无统计学意义(P>0.05);不完全KD患儿CAL发生率高于典型KD组(χ2=5.36,P<0.05)。结论:不完全KD更易发生CAL,卡疤红斑和肛周充血脱屑可作为不完全KD诊断的辅助依据。

Objective： To summarize the clinical characteristics of incomplete Kawasaki. Methods： The main clinical manifestations, and other systemic symptoms, laboratory indicators, the number of cases who had no response when treating with immunoglobulin and coronary artery involvement （CAI） rates of 67 cases with incomplete Kawasaki and 81 cases with complete Kawasaki disease were ana- lyzed. Results： The incidences of the card scar erythema, perianal redness and desquamation, and CAI in incomplete Kawasaki group were higher than complete Kawasaki group （P 〈 0.05 ）. No signifi- cant difference was found in other clinical symptoms, laboratory indicators, and the number of cases who had no response when treating with immunoglobulin between the two groups （P 〉 0.05 ）. Conclu- sions： incomplete Kawasaki is more susceptible to CAI. Card scar erythema, perianal redness and des- quamation may serve as the basis for auxiliary diagnosis.