分析胱抑素C在甲亢治疗中的价值

Analysis of the value of cystatin C on hyperthyroidism

目的 分析胱抑素C （CysC）在131Ⅰ治疗甲状腺功能亢进（甲亢）中的临床应用价值.方法 选择2012年1月至2013年9月于日照市人民医院行131Ⅰ治疗的53例甲亢患者为甲亢组,并选取50例健康者为对照组,测定并比较两组甲状腺激素、血清CysC水平,观察甲亢组患者行131Ⅰ治疗后3个月以及6个月的甲状腺激素、血清CysC水平的变化情况.结果 甲亢组治疗前血清CysC水平较正常人群增高,治疗后甲状腺激素及CysC水平逐渐恢复至正常,组间比较差异有统计学意义（P＜0.05）.结论 血清CysC可以作为甲亢治疗的辅助检测项目,对甲亢治疗的进展程度作出评价.

Objective To analyze the alue of cystatin C （CysC） on 131Ⅰ treatment of hyperthyroidism.Methods Fifty three cases of hyperthyroidism patients who received 131Ⅰ treatment in people＆#39;s hospital of Rizhao from January 2012 to September 2013 were selected as the observation objects and another 50 healthy people were selected as control group.Thyroid hormone and serum CysC levels of the two groups were tested and compared,and the changes of thyroid hormone and serum CysC levels of hyperthyroidism group after treatment for 3 months and 6 months were also observed.Results Serum CysC levels was higher in patients with hyperthyroidism than that in the normal group,but with thyroid hormone level decreasing,and returning to normal levels after 131Ⅰ therapy,serum CysC levels also decreased and returned normal.There was statistical difference between the two groups （P 〈 0.05）.Conclusions Serum CysC can be used as an auxiliary test items in treatment of hyperthyroidism,and thus to evaluate the progress of treatment.