药物治疗合并康复训练对精神分裂症患者的疗效观察

Clinical Observation of Drugs Combined with Rehabilitation Training in the Treatment of Schizophrenia

目的:探讨药物治疗合并康复训练对精神分裂症患者的疗效和对社会功能的影响。方法:160例精神分裂症患者按入院时间顺序分为对照组和观察组各80例;对照组仅采取药物治疗,观察组在药物治疗同时合并劳动技能训练、生活技能训练、健康教育等综合性康复训练措施;疗程均为8周。治疗前后采用简明精神症状评定量表(BPRS)、住院患者康复疗效量表(IPROS)进行临床疗效和社会功能评定并比较两组评分变化和疗效。结果:治疗后,两组BPRS和IPROS评分从第4周起均较前明显降低(P<0.05),且观察组降低幅度明显大于对照组(P<0.05)。两组BPRS和IPROS评分疗效比较,差异无统计学意义(P>0.05),但观察组BPRS和IPROS评分有效率均明显高于对照组(P<0.05)。结论:药物治疗合并康复训练能显著改善精神分裂症患者的精神症状、生活社交能力及认知功能,优于单纯药物治疗。

Objective：To study the efficacy of drugs combined with rehabilitation training in the treatment of schizophrenia and the influence on social function. Methods：Totally 160 cases of schizophrene were divided into the control group and the observation group according to the admission time sequence with 80 ones in each. The control group was treated with medicines, and the observation group was given labor skills training, life skills training and health education additionally. The treatment course was 8 weeks. Before and after the treatment, brief psychiatric rating scale （ BPRS） and inpatient rehabilitation efficacy rating scale （ IPROS） were used to evaluate the clinical efficacy and social function of the two groups, and the score changes and curative effect in the two groups were compared. Results：After the treatment, BPRS and IPROS in the two groups were significantly decreased from the fourth week （ P〈0. 05）, and the reduction degree in the observation group was significantly larger than that in the control group （P〈0. 05）. There was no statistically significant difference in BPRS and IPROS of efficacy between the two groups （P〉0. 05）, while BPRS and IPROS of ef-fective rate in the observation group were significantly higher than those in the control group（P〈0. 05）. Conclusion：Drugs combined with rehabilitation training in the treatment of schizophrenia patients can improve mental symptoms, social life ability and cognitive function, which is better than drug treatment alone.