山西地区上消化道双原发癌34例临床特征分析

The clinical characteristics of upper gastrointestinal multiple primary cancer in Shanxi Province

目的:通过对山西省肿瘤医院34例上消化道双原发癌患者的临床病理资料进行回顾性分析,分析山西地区上消化道双原发癌的发病规律、诊治策略和预后因子。方法:收集上消化道双原发癌病例及数据,分析山西地区上消化道双原发癌的相关临床特征。结果:在纳入的1087例消化系统肿瘤患者中,发现双原发癌34例,发生率为3.13%,癌灶均集中于食管、贲门、胃体三大部位。结论:山西地区的上消化道双原发癌有明显的地域集中分布性,早期诊断后施行同期手术,并结合放化疗等综合治疗可明显提高疗效和改善预后。

Objective： By analyzing the clinical pathology data of the 34 patients with upper gastrointestinal multiple primary cancer in Shanxi cancer hospital,the incidence regularity,diagnosis strategies and prognostic factors was studied. Methods： By collecting the patients and conducting the data,the clinical features with upper gastrointestinal multiple primary cancer in Shanxi was discussed. Results： In a total of 1 087 patients with digestive cancers,34 of 1 087（ 3. 13%） had double primary cancers,and the leading cancer sites were esophagus,cardia and gastric parts. Conclusion： It was found that the upper gastrointestinal double primary cancer in Shanxi has obvious geographical concentration distribution,and the treatment should be based on radical surgery,combined with the radiotherapy and chemotherapy.