摘要
目的：探讨冠状动脉内应用替罗非班在急性心肌梗死急诊经皮冠状动脉介入治疗（ Percutaneous Coronary Interven-tion,PCI）中的临床效果。方法：收集2012年11月～2014年5月于本院治疗的急性心肌梗死的75例患者为研究对象,将其随机分为观察组39例和对照组36例,观察组予PCI后冠状动脉内应用替罗非班治疗,对照组予PCI后静脉内应用替罗非班治疗,然后对2组患者术后心肌再灌注指标、术后1周心功能指标、术后1个月内心脏不良事件进行统计及比较。结果：对比2组术后心肌再灌注指标、心脏不良事件,均P〈0.05,存在统计学差异,术后1周心功能指标P〉0.05,无统计学意义。结论：冠状动脉内应用替罗非班在急性心肌梗死急诊PCI中的临床效果,明显优于静脉内应用替罗非班,建议在临床上推广应用。
Objective：To investigate clinical effect of the intracoronary application for tirofiban in acute myocardial infarction after percutaneous coronary intervention （PCI）. Method： from 2012 November ～2014 year in May,75 cases were collected in the hospital treatment of acute myocardial infarction patients as the research object, then they were randomly divided into observation group of 39 cases and 36 cases in the control group, the observation group for tirofiban treatment with PCI after intracoronary application, control group was given PCI after intravenous application of tirofiban treatment, and 2 groups of patients after myocardial reperfusion index, 1 weeks after the operation, heart function index, after 1 months of statistics and adverse cardiac events. Results：the two groups were compared after marker of myocardial reperfusion, cardiac adverse events, all P〈0. 05, there was significant difference, 1 weeks after the operation, heart function indexes of P〉0. 05, no statistical significance. Conclusion：in the clinical effect,the application of tirofiban in acute myocardial infarction of PCI in the coronary artery, is obviously better than that of intravenous application for tirofiban, recommended in clinical application.
出处
《中国伤残医学》
2015年第6期103-104,共2页
Chinese Journal of Trauma and Disability Medicine
