摘要
目的探讨老年2型糖尿病合并慢性阻塞性肺疾病(COPD)患者胰岛素抵抗和胰岛素功能情况。方法选取2011年3月至2013年3月我院门诊收治的2型糖尿病合并COPD患者50例为观察组,同期选取体检正常者44例为对照组,对两组研究对象的空腹胰岛素、空腹C肽、餐后胰岛素及糖负荷2 h C肽等指标进行检测比较。结果两组患者统计结果显示,观察组患者在胰岛素抵抗上较对照组明显上升,胰岛B细胞功能明显降低,空腹胰岛素、空腹C肽等观察指标与对照组比较,差异均有统计学意义(均P<0.05)。结论老年2型糖尿病合并COPD患者临床表现为胰岛素抵抗,胰岛β细胞功能下降,对此需要在临床治疗中给予积极的治疗和控制。
Objective To explore the conduction elderly patients with chronic obstructive pulmonary emphysema and insulin resistance in patients with type 2 diabetes mellitus insulin function.Methods Type 2 diabetes from 2011March to 2013 March treated in our hospital with chronic obstructive pulmonary disease patients and 50 cases of the observation group, meanwhile 44 healthy subjects as control group,two groups of patients on insulin of fasting insulin,fasting C peptide,and 2 h postprandial C peptide were detected and compared.Results Two sets of statistics showed that in type 2 diabetic patients with COPD in insulin resistance is obviously increased,the function of islet beta cells decreased obviously,compared the fasting insulin,C peptide as observation indexes,the difference was statistically significant（P〈0.05）.Conclusion The insulin resistance and clinical manifestation in patients with chronic obstructive pulmonary disease in elderly type 2 diabetes mellitus,islet beta cell function decline,which need to be treated and control active in clinical treatment.
出处
《中国药物经济学》
2015年第2期137-138,共2页
China Journal of Pharmaceutical Economics
