小儿9项呼吸道感染病原体IgM抗体检测结果分析

Analysis of the Ig M test results of nine respiratory tract infection pathogens in children

目的通过对呼吸道感染患儿的血清Ig M测定,了解郑州地区小儿9项呼吸道病原体感染情况。方法采用间接免疫荧光法,对285例呼吸道感染患儿的9种病原体Ig M抗体同时进行检测。结果 285例患儿中检出Ig M抗体阳性183例,阳性率为64.3%。其中肺炎支原体101例,占35.4%;乙型流感病毒45例,占15.8%;副流感病毒(1型、2型、3型)27例,占9.5%;腺病毒7例,占2.5%;肺炎支原体和乙型流感病毒混合感染29例,占10.2%;肺炎支原体和副流感病毒(1型、2型、3型)混合感染17例,占6.0%;肺炎支原体和腺病毒混合感染4例,占1.4%;肺炎支原体和呼吸道合胞病毒,肺炎支原体、腺病毒和副流感病毒(1型、2型、3型),肺炎支原体、甲型流感病毒和乙型流感病毒,肺炎支原体、乙型流感病毒和副流感病毒(1型、2型、3型)混合感染各1例,占0.4%。结论肺炎支原体和乙型流感病毒是本地区小儿呼吸道感染的主要病原体,且肺炎支原体易与其他病原体混合感染。

Objective The serum Ig M in children with respiratory tract infection were determined in order to investigate the distribution of 9 respiratory pathogens from respiratory infection children in Zhengzhou. Methods The serum specimen were collected from 285 children with respiratory tract infection hospitalized in the department of pediatric and indirect fluorescence immunoassay was used to simultaneously test the antibodies of 9 respiratory pathogens of Ig M. Legionella pneumophila： type1（ LP1）,mycoplasma pneumoniae（ MP）,qrickettsia（ COX）,chlamydia pneumoniae（ CP）,adenovirus（ ADV）,respiratory syncytial virus（ RSV）,influenza virus A（ INFA）,influenza virus B（ INFB）,parainfluenza virus（ 1,2,3）（ PIVs） of the children＇s samples. Results A total of 285 samples were detected,and 183 cases were positive,with a positive rate of64. 3%,the positive rate of MP was 35. 4%（101 cases）,INFB was 15. 8%（45 cases）,PIVs was 9. 5%（27 cases）,ADV was 2. 5%（7 cases）. MP ＋ INFB was 10. 2%（29 cases）,MP ＋ PIVs was 6. 0%（17 cases）,MP ＋ ADV was 1. 4%（4 cases）,MP ＋ RSV,MP ＋ ADV ＋ PIVs,MP ＋ INFA ＋ INFB and MP ＋ INFB ＋ PIVs were 0. 4%（ 1 cases）,respectively. Conclusion MP and INFB are major pathogen infection of children in Zhengzhou,and MP are easily co- infection with other pathogen.