超早期颅骨修补术对外伤性颅骨缺损患者神经功能及生活质量的影响

Effect of early cranioplasty on nerve function and life quality of patients with traumatic skull

目的研究超早期颅骨修补术对外伤性颅骨缺损患者神经功能及生活质量的影响。方法将2012年5月-2014年3月我院收治的外伤性颅骨缺损患者120例纳入研究对象,进行颅骨修补术治疗,根据手术时机不同分为接受超早期手术的观察组和常规时机手术的对照组,比较两组患者的神经功能、神经细胞因子、生活质量情况。结果观察组患者的CSS评分和NIHSS评分（14.76±2.29、16.61±2.35）明显低于对照组;血清NTF和NGF含量（114.38±16.52、6.22±0.91）ng/ml明显高于对照组;物质生活维度、躯体健康维度、心理健康维度、社会功能维度评分（64.75±8.14、75.48±8.32、78.36±8.75、77.34±8.42）明显高于对照组。结论超早期颅骨修补术有助于改善神经功能,提高血清中神经细胞因子和整体生活质量。

Objective To study the effect of early cranioplasty on nerve function and life quality of patients with traumatic skull defect.Methods 120 cases patients with traumatic skull defect in our hospital from 2012May- 2014 March were enrolled in the study and given cranioplasty treatment.Patients were divided into observation group given early operation and control group given routine time operation according to different time of operation.Then neurological function,neural cell factor,quality of life of two groups were compared.Results Observation group CSS score and NIHSS score（14.76±2.29,16.61±2.35）were significantly lower than that control group;serum NTF and NGF levels（114.38±16.52,6.22±0.91）ng/ml were significantly higher than that control group;material life,physical health,mental health,social function（64.75±8.14,75.48±8.32,78.36±8.75,77.34±8.42）were significantly higher than that control group.Conclusion Early cranioplasty is helpful to improve nerve function,increase nervous cytokines and overall quality of life;it＇s an ideal method in treating traumatic skull defect.