氟化漆氯已定凝胶联合应用降低SECC患儿龋齿复发率的疗效观察

Fluoride varnish comblined with chlorhexidine gel reduces the recurrence of severe early childhood caries

目的:评估氟化漆氯已定凝胶联合作用降低重度早期儿童龋(SECC)复发率的临床效果。方法:选择SECC患儿100名,随机分为2组(n=50),实验组采用氟化漆与氯已定凝胶联合作用的方法,对照组则不使用任何药物;比较两组SECC复发率变化情况。结果:SECC累计复发率在6个月时,实验组和对照组分别为6.12%和25.58%;12个月时,实验组和对照组分别为13.04%和33.33%;18个月时,实验组和对照组分别为21.95%和57.50%;2年时,实验组和对照组分别为32.50%和72.22%;各时间点两组SECC累计复发率相比均有统计学差异(P<0.05)。结论:采用氟化漆与氯已定凝胶联合作用的方法可有效降低SECC复发率。

AIM： To evaluate the clinical effect of combined application of fluoride varnish and chlorhexidine gel in reducing the recurrence of severe early childhood caries（ SECC）. METHODS： 100 children with SECC were randomly divided into 2 groups. The children in treatment group received fluoride varnish and chlorhexidine gel treatment,those in control group received no treatment. The children were followed- up for 2 years at 6 m intervals.RESULTS： The recurrence rate of treatment group and control group at 6 m,12 m,18 m and 24 m were 6. 12% vs25. 58%（ P〈0. 05）,13. 04% vs 33. 33%（ P〈0. 05）,21. 95% vs 57. 50%（ P〈0. 05） and 32. 50% vs 72. 22%（ P〈0. 05）,respectively. CONCLUSION： A combination of fluoride varnish and chlorhexidine gel can reduce the recurrence of SECC.