妥洛特罗贴剂穴位透入治疗儿童咳嗽变异性哮喘的临床疗效

Clinical research of tulobuterol tape in children with cough variant asthma

目的:评价妥洛特罗贴剂治疗咳嗽变异性哮喘的临床疗效。方法:将120例咳嗽变异性哮喘患儿随机分成治疗组和对照组,每组各60例。在常规治疗基础上,对照组给予孟鲁司特,治疗组予妥洛特罗贴剂穴位联合孟鲁司特。比较两组症状评分、症状总积分改善的百分率、呼气峰流速(PEF)评分。结果:治疗组的症状评分明显下降,与对照组比较差异有统计学意义(P<0.05);治疗组总积分改善的百分率在观察后期达到临床控制,与对照组比较差异有统计学意义(P<0.05);两组PEF评分差异无统计学意义(P>0.05)。结论:妥洛特罗贴剂穴位治疗咳嗽变异性哮喘疗效显著。

Objective：To evaluate the efficacy of tulobuterol tape in children with cough variant asthma.Methods：A total of 120 children with cough variant asthma were randomly divided into treatment group and control group.Control group was given montelukast,the treatment group was given tulobuterol tape combined with montelukast at bedtime.The symptom scores,percentage of improvement in total symptom score and peak expiratory flow（PEF）scores were compared between the two groups.Results：After 14 days treatment,the symptom scores were significantly decreased in treatment group than that in control group,the percentage of improvement in total symptom score was significantly different between the two groups（P〈0.05）.There was no significant difference in PEF scores between the two groups（P〉0.05）.Conclusion：Tulobuterol tape is effective in treatment of cough variant asthma.