C臂锥形束CT颅内血肿体积定量测量的实验研究

Experimental study of measuring cerebral hemorrhage with C-arm cone-beam CT

目的探测C臂锥形束CT对颅内血肿的定量检测能力。方法于小气球内装对比剂与水的混合物模拟颅内血肿,并按体积分为9组,每组分别接受3次MSCT和3次C臂锥形束CT扫描,将两种成像技术所得图像进行MPR,采用西门子公司的体积测量软件对每组测量3次,计算与真实体积的偏差度,并进行统计学分析。结果对于形态规则的血肿,C臂锥形束CT测量血肿体积的准确率较高,与实际血肿体积和MSCT相比差异均无统计学意义（P〉0.05）。对于形态不规则的血肿,在测量〈30ml或〉60ml的血肿体积时,C臂锥形束CT测量体积与实际体积相比存在误差（P〈0.05）;测量体积为30-60ml血肿时,C臂锥形束CT测量体积与实际体积基本一致（P〉0.05）;MSCT测量体积准确率明显高于C臂锥形束CT（P〈0.05）。结论合理选择C臂锥形束CT颅内血肿定量检测范围,在介入诊治中有效监测颅内出血。

Objective To explore the ability of measuring cerebral hemorrhage volume by C-arm cone-beam CT（DynaCT）.Methods The mixture of contrast agent and water was packaged with small balloon simulated intracranial hematoma,which were divided into 9groups by the volume.Each group received 3times scanning by MSCT and DynaCT respectively,and MPR images were reconstructed.All the volume were measured with Siemens Volume Measurement software,and the degree of deviation were calculated.Results When the shape of hematoma was regular,the accuracy of DynaCT was high,which had no significant statistical defference compared to those of actual volume and MSCT（P〉0.05）.When the shape of hematoma was irregular and the volume was less than 30 ml and more than 60 ml,there was statistical difference of volume between actual volume and measuring volume with DynaCT（P〈0.05）,when the shape of hematoma was irregular and volume was 30—60ml,the measurement volume with DynaCT was equal to the actual volume（P〉0.05）.The accuracy of measuring cerebral hematoma with MSCT was higher than that of DynaCT（P〈0.05）.Conclusion The reasonable choice of quantitative detection range of intracranial hematoma with DynaCT could be effectively applied to the monitoring of the intracranial hemorrhage during interventional diagnosis and treatment.