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组织因子在恶性肿瘤中的研究进展 被引量:3

Progression of tissue factor in the malignant tumor
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摘要 组织因子作为凝血因子Ⅶ细胞膜表面受体启动外源性凝血途径,参与肿瘤的高凝状态,并且在多种恶性肿瘤中高表达,介导多种信号转导影响肿瘤的生长、转移。 Tissue factor conducts as cell surface receptor for coagulation factor Ⅶ to initiate extrinsic coagulation pathway,involving in tumor hypercoagulable state. Whatˊs more,it is highly exprssed in multiple cancers,and medi-ates multiple signal transduction to affect tumor growth and metastasis.
出处 《现代肿瘤医学》 CAS 2015年第5期709-712,共4页 Journal of Modern Oncology
关键词 组织因子 肿瘤 血栓形成 生长 肿瘤转移 thromboplastin neoplasm thrombosis growth neoplasm metastasis
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  • 1Kocattirk B,Versteeg HH. Tissue factor isoforms in cancer and co- agulation : May the best isoform win [ J ]. Thromb Res, 2012,129 : $69 - $75.
  • 2Schaffner 17, Yokota N, Ruf W. Tissue factor proangiogenic signaling in cancer progression[J]. Thromb Res,2012,129 :S127 - S131.
  • 3Magnus N, Gamier D, Meehan B, et al. Tissue factor expression provokes escape from tumor dormancy and leads to genomie altera- tions[ J ]. Proe Natl Acad Sci USA ,2014,111:3544 - 3549.
  • 4Anand M, Brat DJ. Oneogenic regulation of tissue factor and throm- bosis in cancer[ J]. Thromb Res ,2012,129 : $46 - $49.
  • 5Yu JL, May L, Lhotak V, et al. Oncogenic events regulate tissue fac- tor expression in eolorectal cancer cells:Implications for tumor pro- gression and angiogenesis [ J ]. Blood,2005,105 : 1734 - 1741.
  • 6Rao B, Gao Y, Huang J, et al. Mutations of p53 and K - ras corre- late TF expression in human colorectal carcinomas:TF downregula- tion as a marker of poor prognosis[ J]. Int J Colorectal Dis,2011, 26:593 - 601.
  • 7Yu JL, Xing R, Milsom C, et al. Modulation of the oncogene - de- pendent tissue factor expression by kinase suppressor of ras 1 [ J ]. Thromb Res,2010,126 : e6 - elO.
  • 8Rong Y, Belozerov VE, Tucker - Burden C, et al. Epidermal growth factor receptor and PTEN modulate tissue factor expression in glio- blastoma through JunD/activator protein - 1 transcriptional activity [ J]. Cancer Res ,2009,69:2540 - 2549.
  • 9Kato S,Pinto M,Carvajal A,et al. Tissue factor is regulated by epi- dermal growth factor in normal and malignant human endometrial epithelial cells [J]. Thromb Haemost,2005,94:444 - 453.
  • 10Milsom CC,Yu JL, Mackman N, et al. Tissue factor regulation by epidermal growth factor receptor and epithelial - to - mesenchymal transitions:Effect on tumor initiation and angiogenesis[J]. Cancer Res ,2008,68 : 10068 - 10076.

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