干扰素α-1b联合甘草酸苷(美能)对流行性腮腺炎治疗效果

Interferon alpha 1 b joint glycyrrhizic acid glycosides(mae) for the treatment of mumps

目的:观察干扰素α-1b联合甘草酸苷(美能)对流行性腮腺炎的治疗效果。方法:选择100例流行性腮腺炎患者,将其随机分为观察组与对照组各50例。观察组给予干扰素α-1b 100万IU肌肉注射,1次/d,联合复方甘草酸苷注射液5~20ml加入200ml生理盐水中静脉滴注,1次/d,连用3~5d。对照组给予板兰根冲剂5~10g/次,3次/d,以及利巴韦林10~15 mg/kg静脉滴注,1次/d,连用3~5d。观察两组患者的治疗效果。结果:两组患者均全部治愈,治愈率100%。观察组患者在发热消退时间、消肿时间等方面均明显优于对照组(P<0.05)。结论:干扰素α-1b联合甘草酸苷治疗流行性腮腺炎疗效确切、见效快,值得临床推广使用。

Objective： Observation of interferon alpha 1 b joint glycyrrhizic acid glycosides （mac） for the treatment effect of mumps. Methods： 100 cases of our hospital patients with mumps were chosen and randomly divided into ob- servation group and control group 50 cases each. Observation group was given interferon alpha 1 b 1 million IU intramuscular injection, once a/d, joint glycosides compound glycyrrhizin injection in 5 ^-20 ml to 200 ml saline intravenous drip, 1 / d, amuse （3 ~ 5 d）.The control group given radix isatidis infusion of 5 - 10 g/time, 3 times/d, and ribavirin 10 ~ 15 mg/kg intravenous drip, 1 / d, amuse （3 ~ 5 patients. Results： two groups of patients were all cured, the cure d）.To observe the therapeutic effect of two groups of rate was 100%.Observation group of patients in the fever subsided, swelling time were significantly better than that in control group （P〈 0.05）.Conclusion： Interferon alpha 1 b combined with glycyrrhizin glueoside of mumps proves exact curative efficacy and quick effect, whichi is worthy of clinical use.