癫痫病灶检测技术的研究进展

Research progress in epileptogenic focus detection

癫痫病灶检测技术已成为治疗难治性癫痫的一种重要手段,病灶的准确检测是保证手术安全、取得良好疗效的关键。本文综述了癫痫病灶检测技术的新进展,包括脑电图(electroencephalogram,EEG)、常规磁共振(magnetic resonance imaging,MRI)、功能性磁共振(functional magnetic resonance imaging,f-MRI)、同步脑电联合功能磁共振成像(electroencephalogram-functional magnetic resonance imaging,EEG-f MRI)、磁共振波谱分析(magnetic resonance spectroscopy,MRS)、脑磁图(magnetoencephalogram,MEG)、磁源性影像(magnetic source imaging,MSI)、单光子发射计算机断层扫描(single photon emission computed tomography,SPECT)、正电子发射断层扫描-计算机断层成像(positron emission tomography-computed tomography,PET-CT)以及偶极子定位(dipole localization method,DLM)等检测方法,并分析了每种方法的优缺点及发展方向。

Epileptogenic focus detection has become an important method of treatment for refractory epilepsy. Accurate detection is the key to ensure the safety of surgery and achieve good curative effect. This paper mainly summarizes the recent progress in epileptogenie focus detection, including EEG, MRI, f-MRI, EEG-fMRI, MRS, MEG, MSI, SPECT, PET-CT and DLM, then analyzes the advantages, disadvantages and the development direction of each method.