血浆致动脉硬化指数与高血压的相关性研究

Study of relationship between atherogenic index of plasma and hypertension

目的:探讨血浆致动脉硬化指数(AIP)与高血压之间的关系。方法:3 824例健康体检人群根据血压分为高血压组和血压正常组,分析比较两组间的三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及血浆致动脉硬化指数。按AIP四分位数分析与高血压的关系。结果:高血压组的AIP、TG、TC、LDL-C显著高于血压正常组,HDL-C低于血压正常组(P<0.05)。高四分位AIP中高血压的发生率是低四分位的2倍多(P<0.05)。高血压患者中TG、HDL-C、TC、舒张压是AIP的影响因素。结论:AIP与高血压关系密切,能更准确预测高血压病患者发生动脉粥样硬化的风险。

Objective To study the relationship between atherogenic index of plasma and hypertension. Method According to the blood pressure 3 824 cases of healthy population were divided into hypertension group and normal blood pressure group,the triglyceride（ TG）,total cholesterol（ TC）,high density lipoprotein cholesterol（ HDL-C）,low density lipoprotein cholesterol（ LDL-C） and atherogenic index of plasma between the two groups were compated,then we analyzed the changes of hypertension by quartile of AIP. Results AIP、TG、TC、LDL-C in hypertension group were significantly higher than in normal blood pressure group,but HDL-C was lower（ P 〈0. 05）. The incidence rate of hypertension in the high quartile of AIP was two times more than the low quartile of AIP（ P〈 0. 05）. TG、HDL-C、TC、diastolic pressure was the affecting factors of AIP in patients with hypertension. Conclusion AIP has a close relationship with hypertension and can more accurately predict the risk of atherosclerosis in patients with hypertension.