地佐辛超前镇痛对开胸患者术后认知功能的影响分析

Postoperative cognitive function effects of Dezocine preemptive analgesia for thoracic surgery patient

目的:探讨地佐辛超前镇痛对开胸患者术后认知功能的影响。方法:择期行开胸手术患者80例,根据随机抽签原则分为治疗组与对照组各40例,所有患者手术结束时接电子镇痛泵行静脉自控镇痛,治疗组的镇痛泵药物为地佐辛,对照组为舒芬太尼。结果:治疗组镇痛后6 h、12 h、24 h的疼痛评分与对照组对比,差异无统计学意义,两组均有较好的镇痛效果(P>0.05)。镇痛后24 h进行调查,治疗组的MMSE评分明显高于对照组,对比差异明显(P<0.05)。结论:地佐辛超前镇痛应用开胸患者术后能发挥很好的镇痛效果,同时对于术后认知功能影响小,值得推广应用。

Objective To investigate the postoperative cognitive function effects of Dezocine preemptive analgesia for thoracic surgery patient. Method 80 cases with undergoing elective thoracic surgery in accordance with the principles of the draw were equally divided into the treatment group and the control group,all patients were received electronic analgesia intravenous analgesia after surgery,the analgesia drugs of the treatment group were dezocine,so that were sufentanil in the control group. Results The Postoperative 6h,12 h and 24 h pain scores of the treatment group in comparison with the control group had not statistically significant,both groups had good analgesic effect（ P〉 0. 05）. 24 h post-analgesic investigation,the MMSE scores of the treatment group were significantly higher,compared to significant differences（ P〈 0. 05）. Conclusion The application of Dezocine preemptive analgesia for thoracic surgery patient can play better analgesic effect,while have little effects for postoperative cognitive function that should be widely applied.