mPCNL术后尿源性脓毒血症危险因素研究

Risk factors for urosepsis after minimally invasive percutaneous nephrolithotomy

目的了解患者微创经皮肾镜取石术（mPCNL）术后发生尿源性脓毒血症的相关危险因素。方法收集某院1 022例患者mPCNL围手术期的临床资料,对患者mPCNL术后发生尿源性脓毒血症的危险因素进行分析。结果 1 022例患者,发生尿源性脓毒血症62例,发生率为6.07%。患者经早期发现、积极治疗后均痊愈出院。logistic逐步回归分析,结果显示,年龄（OR95%CI：1.25-3.92）、血常规（OR95%CI：1.25-14.00）、尿常规（OR95%CI：2.67-10.02）及术中灌注液体量（OR95%CI：1.37-4.18）与尿源性脓毒血症的发生密切相关。结论年龄（≥60岁）和术中灌注液体量（≥30 L）是患者mPCNL术后发生尿源性脓毒血症的危险因素;了解相关危险因素,有助于预防和及时治疗患者mPCNL术后尿源性脓毒血症。

Objective To explore the risk factors for urosepsis after minimally invasive percutaneous nephrolithot-omy（mPCNL）.Methods Clinical data of 1 022 patients undergoing mPCNL were collected,risk factors for urosep-sis after mPCNL were analyzed.Results Of 1 022 patients,62 （6.07%）developed urosepsis.All patients recov-ered and discharged after early diagnosis and active treatment.Logistic regression analysis showed that age（OR95%CI ：1 .25-3.92）,blood routine examination （OR95%CI ：1 .25-14.00）,urine routine examination（OR95%CI ：2.67-10.02）and volume of intraoperative fluid perfusion（OR95%CI ：1 .37-4.18）were closely related to urosepsis fol-lowing mPCNL.Conclusion Age（≥60 years）and intraoperative perfusion fluid volume （≥30L）during operation are the risk factors for urosepsis following mPCNL,The recognition of the related risk factors is helpful for the pre-vention and timely treatment of urosepsis following mPCNL.