老年冠心病患者冠状动脉狭窄及血脂代谢与幽门螺杆菌感染的相关性

Relation of coronary stenosis and lipid metabolism in patients with coronary heart disease and Helicobacter pylori infection

目的探讨老年冠心病患者冠状动脉狭窄、血脂代谢与幽门螺杆菌感染的相关性。方法选取我院2010年4月~2013年4月收治的144例幽门螺杆菌感染者作为研究对象,将其中72例老年冠心病患者作为观察组,另外72例无老年冠心病的患者作为对照组,观察两组在冠状动脉狭窄和血脂代谢血清总胆固醇（TC）、血清甘油三酯（TG）、血清高密度脂蛋白胆固醇（HDL-C）、血清低密度脂蛋白胆固醇（LDL-C）的差异性。结果对照组HP阳性数17例,检出率为23.61%;观察组HP阳性数39例,检出率为54.17%。对照组Gensini评分为（19.2±12.1）分,Hcy为（10.46±1.72）μmol/L;观察组Gensini评分为（34.6±27.3）分,Hcy为（16.13±4.23）μmol/L,两组比较差异有统计学意义（均P〈0.05）;另外,两组在血脂水平TC、TG、HDL-C、LDL-C上比较差异亦有统计学意义（均P〈0.05）。结论老年冠心病患者冠状动脉狭窄、血脂代谢与幽门螺杆菌感染存在相关性,在临床治疗时要注意关注。

Objective To investigate coronary stenosis in patients with coronary artery disease lipid metabolism associated with Helicobacter pylori infection,so as to improve the level of clinical diagnosis and treatment of coronary heart disease.Methods 72 patients with coronary heart disease and 72 patients without coronary artery diseases were included in the present study.The coronary artery stenosis and total serum lipid cholesferol（TC）,serum triglyceride（TG）,high density lipoproteins cholesterol（HDL-C）and low density cholesterol（LDL-C）were observed.Results The positive rate of HP of research group and control group were 23.61% and 54.17%.The Gensini score of research group and control group were 34.6±27.3and 19.2±12.1.TC,TG,HDL-C and LDL-C of the two groups were significantly diffirent（P〈0.05）.Conclusion Patients with coronary heart disease coronary stenosis lipid metabolism correlated with Helicobacter pylori infection treatment should be noted in the clinical concern.