左旋氨氯地平联合心理干预对高血压伴更年期综合征患者的临床效果

Clinical observation of levamlodipine combined with psychological intervention for hypertension patients with climacteric syndrome

目的观察左旋氨氯地平联合心理干预对高血压伴更年期综合征（Climacteric syndrome,CS）患者的临床效果。方法选取2012年7月~2013年7月接受治疗的高血压伴CS患者120例作为研究对象。根据数字表法随机分成观察组和对照组各60例。对照组患者单纯应用左旋氨氯地平治疗,观察组在对照组治疗方法的同时进行心理干预。对比两组患者治疗前后的血压变化、疗效及心理情绪评分。结果观察组治疗后的24hSBP、24hDBP、dSBP及nSBP水平均显著低于对照组,差异均有统计学意义（均P〈0.05）。但两组dDBP与nDBP对比,差异无统计学意义（P〉0.05）。观察组的总有效率为95.00%（57/60例）,显著高于对照组的83.33%（50/60例）,差异有统计学意义（P〈0.05）。两组治疗后的HAMA与SAS评分均有下降,但观察组的下降幅度显著高于对照组,差异均有统计学意义（均P〈0.05）。结论对高血压伴CS患者联合使用左旋氨氯地平与心理干预,具有更好的疗效,可在临床推广应用。

Objective To discuss clinical effect of levamlodipine combined with psychological intervention for hypertension patients with climacteric syndrome.Methods 120 patients with hypertension with CS were divided into observation group（60 cases）and control group（60 cases）.Control group patients were treated with levorotatory amlodipine.The observation group was treated with levorotatory amlodipine and the psychological intervention.The blood pressure before and after the treatment,curative effect and psychological mood score were observed.Results The observation group＇s 24 hSBP,24hDBP and dSBP and nSBP after treatment were significantly lower than control group（P〈0.05）.There was no statistically significant difference of dDBP and nDBP between the two groups（P〈0.05）.Observation group＇s total effective rate（95.00%）was significantly higher than that of control group（83.33%）（P〉0.05）.HAMA and SAS scores of the two groups were decreased after treatment,but the decline in observation group was significantly higher than the control group（P〈0.05）.Conclusion Levamlodipine combined with psychological intervention has curative effect on patients with high blood pressure and CS.