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精氨酸酶抑制剂对血管内皮功能影响的研究进展 被引量：5

Development of arginase inhibitors' influence on vascular endothelial function
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摘要 精氨酸酶在许多心血管疾病中的表达及活性增高,包括缺血再灌注损伤、高血压、动脉粥样硬化等。近年来,精氨酸酶抑制剂的不断研发为心血管疾病的治疗提供了新的思路,本文就精氨酸酶的作用基础、精氨酸酶抑制剂的发展及其对血管内皮功能的影响做一综述。 Arginase expression and activity is upregulated in many cardiovascular diseases including ischemia reperfusion injury,hypertension and atherosclerosis,et al.arginase inhibitors＇ continued development may represent new idea for cardiovascular disease＇s novel therapeutics.This paper reviews the basic role of arginase,the development of arginase inhibitor and its effect on vascular endothelial function.
作者 赵娜 苏赢 马维红
机构地区 桂林医学院附属医院心血管内科 沂水中心医院神经外科
出处 《西部医学》 2015年第3期475-477,共3页 Medical Journal of West China
基金 广西壮族自治区卫生厅中医药科技专项(GZLC14-38)
关键词 NO NOS 精氨酸酶 精氨酸酶抑制剂 血管内皮 NO NOS Arginase Arginase inhibitors Vascular endothelial function
分类号 R544.1 [医药卫生—心血管疾病]
  • 相关文献

参考文献28

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二级参考文献44

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共引文献8

同被引文献31

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引证文献5

二级引证文献21

西部医学
2015年 第3期

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