七氟醚、地氟醚静吸麻醉诱导气管插管对眼压及血流动力学的影响

Inflence of sevoflurane and desflurane tracheal intubation intravenous inhalational anesthesia

目的：研究使用相同静脉麻醉药分别吸入七氟醚和地氟醚行麻醉诱导气管插管对眼压及血流动力学的影响。方法：选择年龄6-15岁100例斜视手术患者,随机分为地氟醚组（D组;n=50）和七氟醚组（S组;n=50）。测量麻醉诱导前（B）、诱导后插管前（AI）、插管后1min（T1）、插管后3min（T3）、插管后5min（T5）的眼内压（IOP）和血流动力学参数。结果：IOP组内AI、T1、T3、T5比麻醉诱导前有显著降低,组间比较差异无统计学意义。D组内组间比较差异无统计学意义。S组AI、T1、T3、T5比麻醉诱导前组内显著下降。MAP：T1在S组内升高并低于D组。HR：D组、S组内AI、T1、T3、T5比麻醉诱导前显著增快。D组T1、T3高于S组。结论：组内眼压显著低于麻醉前,组间眼压比较无统计学意义。七氟醚组血流动力学参数稳定,优于地氟醚组。

Objective：To evaluate the difference between two groups inhaling sevoflurane and desflurane to induction with the same intravenous medicines,research the effect of the tracheal intubation to IOP and hemodynamic.Methods：100cases age from 6-15 years old.The patients were divided into two groups at random,namely Group Dn=50used sevoflurane,and Group S n=50used desflurane.Observed IOP and hemodynamic before induction（B）and intubation（AI）,Time point：1,3,5min after intubation.Results：IOP on AI、T1、T3、T5had obvious lower than B,but no significantly difference.D group showed no significantly difference in the both side.S group on AI、T1、T3、T5shows significantly descending.MAP：T1ascended in group S but still lower than group D.HR：Faster in group D、S,AI、T1、T3、T5.T1 and T3in group D was higher than group S.Conclusion：IOP in both groups is obvious lower than pre-anesthesia,but no significantly differences between groups.Statistic shows the group using sevoflurane in hemodynamics stability is better than that group.