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可溶性人白细胞抗原G与胚胎着床相关性研究进展

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摘要 提高体外受精-胚胎移植技术的临床妊娠率,获得高质量的胚胎是胚胎学家为之奋斗的目标。目前评价胚胎质量普遍应用的是形态学观察,尚不能满足准确预测胚胎发育潜能的需要。s HLA-G因其在母-胎界面的独特分布和母-胎免疫耐受中所发挥的重要作用而引起关注,但对于胚胎培养液中s HLA-G能否作为胚胎质量的评价参数,反映胚胎的种植潜能,目前尚无定论。本文综述了国内外近年来胚胎培养液中s HLA-G与胚胎发育以及IVF-ET临床妊娠率的关系研究,努力为临床优选胚胎提供一种有效的非侵入性检测途径,提高妊娠率。
出处 《中国优生与遗传杂志》 2015年第3期7-8,共2页 Chinese Journal of Birth Health & Heredity
基金 首都医科大学附属北京妇产医院青年基金专项资助项目FCYYQN-201407
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