乌鲁木齐地区维吾尔族、汉族男性弱精子症危险因素的研究

The Research of weak sperm risks from Uyghur and Han nationality in Urumqi

目的探讨乌鲁木齐市维吾尔族(以下简称:维族)、汉族男性弱精子症的危险因素,为维、汉族男性弱精子症的病因研究、预防干预及生殖健康服务工作提供依据。方法对维、汉族男性弱精子症患者及维、汉族男性正常健康体检者,进行问卷调查及实验室检查。并将研究对象分为四组,分别为:维、汉族男性弱精子症组,维、汉族男性健康体检组(后称:维、汉族正常组)。分别对维、汉族男性弱精子症组各166人与维、汉族正常组各166人,进行单因素Logistic回归分析,初步筛选出有影响的危险因素,再进行多因素Logistic回归分析,进一步精选出对维、汉族男性弱精子症有极大影响的因素,做出回归方程,并分析危险因素产生的原因。结果 1、对维族弱精子症而言,有关联的危险因素是饮酒史(OR=2.475,95%CI:1.283-4.773);对汉族弱精子症而言,有关联的危险因素是农药接触史(OR=0.454,95%CI:0.195-1.054),棉籽油的食用史(OR=2.115,95%CI:1.250-3.579)。2、维族弱精子症患者使其配偶有流产史不育的危险性高于维族正常组(OR=3.094,95%CI:1.149-8.332)。结论 1、维族男性少精子症而言,有关联的危险因素是末次排精时间;对汉族男性少精子症而言,有关联的危险因素是末次排精时间;对维族男性弱精子症而言,有关联的危险因素是饮酒史;对汉族男性弱精子症有关联的危险因素是农药接触史以及棉籽油的食用史。2、汉、维族男性少精子症患者和维族男性弱精子症患者均可使其配偶有流产。

Objective：This paper is about to study for the risk of the less sperm from Uyghur and Han nationality in Urumqi. Based on the result can be used to support the research of the nosogeny of the sperm less weak risk from the Uyghur and Han nationality which can help to provide the evidence for the reproductive health services. Methods：For Uyghur and han nationality sperm weak spermatozoon disease,and Uyghur and han nationality normal physical examination,questionnaire investigation and laboratory examination. Research object is divided into six groups,respectively is：Uyghur men weak spermatozoon group,the han nationality weak spermatozoon group,the Uyghur and han nationality male physical examination group. Uyghur and han nationality weak spermatozoon disease grouping 4 parts,such like Uyghurs weak spermatozoon disease,Hans weak spermatozoon disease,Uyghur and han nationality male physical examination group each 166 people. Analyzed by univariate logistic regression analysis,initial screening risk factors influential,multivariate Logistic regression analysis,further selection of factors have a great impact for both Uyghur and han nationality weak spermatozoon disease,Make the regression equation,and analyze the causes of the risk factors. Results：1,The risk for the Uyghurs weak spermatozoon disease,is related to the history of alcohol drinking（OR = 2.475,95% CI：1.283-4.773）. The risk for the Han weak spermatozoon disease is related to pesticide exposure history（OR = 0.454,95% CI：0.195-1.054）,and the cottonseed oil edible history（OR = 2.115,95% CI：1.250-3.579）;2,The Uyghur nationality weak spermatozoon disease patients to their spouse has a history of miscarriage risk of infertility is higher than the control group（OR = 3.094,95% CI：1.149-8.332）. 3,Sperm quantity,p H value（p H）,forward movement level sperm counts,sperm and live sperm rate total contributions to the han weak spermatozoon disease is larger;Semen p H value（p H）,the total number of sperm,sperm forward movement,total number of class b,class c total sperm sperm contribution to uyghur weak sperm is larger. Conclusion：1,The risk for the Uyghurs weak spermatozoon disease,is related to the history of alcohol drinking. The risk for the Han weak spermatozoon disease is related to pesticide exposure history,and the cottonseed oil edible history;2,han and Uyghurs less sperm and Uyghurs weak spermatozoon disease can lead to their spouse.