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正交试验优化金银花提取物的真空带式干燥工艺的研究 被引量:7

Optimization of vacuum belt drying process for Lonicerae Japonicae Flos extract by orthogonal test
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摘要 目的优化金银花提取物的真空带式干燥工艺。方法以绿原酸提取率和提取物收率为考察指标,选用干燥温度、履带速度、进料量为考察因素,采用L9(34)正交试验确定金银花提取物最佳真空带式干燥工艺参数。结果最佳干燥工艺条件为:干燥温度60℃,履带速度为175 mm/min,进料量为18 L/h。结论本干燥工艺所得绿原酸的提取率高,提取物收率稳定,适用于金银花提取物大规模的真空干燥工艺使用。 Objective To optimize the vacuum belt drying process for Lonicerae Japonicae Flos extract using orthogonal test. Methods The contents of chlorogenic acid and extract yield were taken as indexes, as well as heating plate temperature, track speed, and feeding speed as factors, the best belt drying process of Lonicerae Japonicae Flos extract was optimized using L9(34) orthogonal test. Results The optimal vacuum belt drying process conditions were as follows: heating plate temperature of 60 ℃, track speed of 175 mm/min, and feeding speed of 18 L/h. Conclusion The chlorogenic acid content is high and the yield is stable, which is suitable for mass production of Lonicerae Japonicae Flos extract using vacuum belt drying process.
出处 《现代药物与临床》 CAS 2015年第2期141-144,共4页 Drugs & Clinic
关键词 金银花提取物 真空带式干燥 正交试验 绿原酸 高效液相色谱 Lonicerae Japonicae Flos extract vacuum belt drying process orthogonal test chlorogenic acid HPLC
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