尿沉渣与干化学联合检测在泌尿生殖系统感染中的应用评价

Application of urine sediments and dry chemical joint detection of urogenital system infections

目的:对尿沉渣与干化学联合检测在泌尿生殖系统感染中的应用展开研究分析。方法:随机选取2012年4月至2014年4月期间我院接收疑为泌尿生殖系统感染患者的500份尿液标本,所有标本均进行尿细菌定量培养,并应用尿沉渣和干化学检测白细胞(WBC)、细菌(BACT)、白细胞酯酶(LEU)、亚硝酸盐(NIT),以尿培养结果为金标准,观察对比检测结果。结果:尿沉渣检测WBC、BACT与定量培养结果对比,无显著性差异,无统计学意义(P>0.05);干化学检测LEU、NIT与定量培养结果对比,差异性显著,具有统计学意义(P<0.05);尿沉渣和干化学联合检测结果与定量培养结果对比,无显著性差异,无统计学意义(P>0.05);尿沉渣与干化学联合检测诊断尿路感染的灵敏度、特异性、总符合率以及阳性预测值、阴性预测值分别为75.8%、94.7%、87.5%、91.2%、84.6%。结论:尿沉渣与干化学联合检测与尿定量培养结果对泌尿生殖系统感染有着高度统一性,对泌尿生殖系统感染早期筛选、诊断有着十分重要的临床价值。

Objectives： To explore the application and evaluation of urine sediments and dry chemical combined detection of urogenital system infections. Methods： 500 urine samples in our hospital from April 2012 to April 2014 were randomly selected. All samples were conducted quantitative bacterial cultures of urine and urinary sediment and dry chemical detection were applied to detect leukocytes（ WBC）,bacteria（ BACT）,leukocyte esterase（ LEU）,nitrite（ NIT）. Taking urine culture results as the gold standard,the results of detection were observed and compared. Results： No statistically significant difference could be found in the comparison of urine detection WBC and BACT（ P〉0. 05）; Dry chemical detection LEU,NIT and quantitative culture results were compared,with statistically significant difference（ P〈0. 05）; comparing the joint test results of urinary sediment and dry chemistry with quantitative culture results,no statistically significant difference could be found（ P〉0. 05）; The sensitivity,specificity,total compliance rate,positive predictive value and negative predictive value of urine combined with dry chemical detection and diagnosis of urinary tract infection were 75. 8%,94. 7%,87. 5%,91. 2%,84. 6% respectively. Conclusion： The urine sediments and dry chemical combined detection has a high degree of uniformity with quantization of urine culture results on the urogenital system infection,hereby of important clinical value in the early screening and diagnosis of urogenital system infection.