急性肾损伤致远隔器官损伤

Remote organ damage following acute kidney injury

急性肾损伤可导致远隔脏器损伤，这些相互作用的机制仍未明确。现通过文献复习，综述了急性肾损伤后心、肝、肺、脑等远隔脏器损伤的不同特点和机制。

Acute kidney injury（AKI） can lead to remote organ damage. The specific mechanism by which the AKI results in distant organ damage is yet to be determined. In animal models,it has become increasingly clear that AKI is not an isolated event but results in remote organ dysfunction involving the heart, lungs, liver, and brain. This review summarizes the effects of AKI on remote organs.