系膜细胞在肾脏损伤中的作用

The role of mesangial cell in kidney injury

肾脏重塑是肾脏对内外因素导致肾损伤的一种反应机制，这种反应有利于控制潜在的威胁生命的危险和恢复体内平衡，包括组织修复、炎性反应以控制感染的风险、上皮修复和瘢痕消除或最小化。肾小球系膜细胞参与了凝血、纤维蛋白溶解、肾小球炎症的启动和系膜增殖性疾病。。肾小球系膜细胞在。肾小球疾病的发生和发展及在控制疾病的危险中起重要作用。

Kidney remodeling is a response to intrinsic or extrinsic triggers of kidney injury. The response po- tentialy control life - threatening dangers and to regain homeostasis, including tissue repair, inflammation to control the risk of infection, epithelial repair, scar resolution or minimization. Mesangial cell involved in clotting, fibrinolysis, trigge- ring glomerular inflammation and mesangioproliferative disorders. Mesangial cell may play an important role in the devo- loping of glomerular diseases and in controlling the risks of these diseases.