老年人肺部感染致多器官功能不全综合征高危人群筛查与随防干预研究

Screening and intervention study on the high risk populations of multiple organ dysfunction syndrome in the elderly caused by pulmonary infection

目的筛查驻石家庄地区军队干休所老年离退休干部肺部感染致老年多器官功能不全综合征(MODSE)的高危人群,并对其进行随防干预,为早期预防老年人肺部感染致MODSE奠定基础。方法采用MODSE早期预测评分系统对驻石家庄地区军队干休所>65岁离退休干部进行肺部感染致MODSE高危人群筛查,将筛查出来的肺部感染致MODSE高危人群按不同干休所随机分为干预组和非干预组,对干预组进行为期1年的随防干预,评价干预效果。结果肺部感染致MODSE高危人群占总筛查人数的20.35%;干预组与非干预组肺部感染发病率差异无统计学意义(χ2=0.003,P=0.954);干预组肺部感染后MODSE发病率显著低于非干预组(χ2=4.709,P=0.03)。结论肺部感染致MODSE高危人群在驻石家庄地区军队干休所老年离退休干部中占有较高的比例,针对肺部感染致MODSE高危人群的相关危险因素进行早期干预,能够明显降低肺部感染后的MODSE发病率。

Objective To screen the high risk populations of multiple organ dysfunction syndrome in the elderly（ MODSE） caused by pulmonary infection living in Shijiazhuang area Cadre Sanatorium and to intervene their risk factors.Methods The physical examination data of retired cadres aged more than 65 years old,who lived in Shijiazhuang area Cadre Sanatorium,were collected and scored by the early prediction score system of MODSE. The aged with a forecast score more than 27. 5 was defined as high risk population of MODSE caused by pulmonary infection. The high risk population of MODSE caused by pulmonary infection were randomly divided into intervention group and non-intervention group.The high risk population of the intervention group received intervention for one year. Results The high risk populations of MODSE caused by pulmonary infection accounted for 20. 35% of the total number,and there was no significant difference between the intervention group and non-intervention group in the pulmonary infection rate（ χ^2= 0. 003,P = 0. 954）.The morbidity of MODSE caused by pulmonary infection in intervention group was more than that in non-intervention group（ χ^2= 4. 709,P = 0. 03）. Conclusions The high risk populations of MODSE caused by pulmonary infection occupy a higher proportion in the elderly veterans living in Shijiazhuang area Cadre Sanatorium. Intervention for the related risk factors of the high risk populations of MODSE caused by pulmonary infection may decrease the morbidity of MODSE.