盐酸左氧氟沙星分子印迹膜电化学传感器的制备及应用

Preparation and Application of Levofl oxacin Hydrochloride Electrode Based on Film of Molecularly Imprinted Polymer

以盐酸左氧氟沙星为目标分子,邻苯二胺和间苯二酚为功能单体,采用循环伏安（CV）法,在玻碳电极表面成功制备了盐酸左氧氟沙星分子印迹聚合膜传感器。采用差分脉冲伏安（DPV）法和CV法考察了所制传感器的性能。峰电流在1.0×10^-9-3.8×10^-7 mol/L范围内与浓度的线性关系良好,检测限为8.2×10^-10 mol/L。

With levofloxacin hydrochloride as the templet, and o-phenylenediamine and m-dihydroxybenzene as the functional monomer, a molecularly imprinted polymer membrane sensor of levofloxacin hydrochloride was prepared on the surface of a glassy carbon electrode by using cyclic voltammetry （CV） electropolymerization method. Electrochemical behavior of the sensor was characterized by CV and differential pulse voltammetry （DPV）. The peak currents of DPV and concentration had a good linear relationship in the range of 1.0×10^-9 - 3.8×10^-7 mol/L, with a detection limit of 8.2×10^-10 mol/L.