妇科再造胶囊联合炔雌醇环丙孕酮片治疗多囊卵巢综合征的疗效观察

Efficacy of Gynecological Reengineering Capsule Combined with Diane 35 for Polycystic Ovary Syndrome

目的:探讨妇科再造胶囊联合炔雌醇环丙孕酮片联合治疗多囊卵巢综合征的临床疗效。方法:将2012年2—8月武汉大学人民医院妇科134例多囊卵巢综合征患者,以随机数字表法分为对照组(68例)与治疗组(66例)。治疗组患者采用妇科再造胶囊与炔雌醇环丙孕酮片联合治疗,对照组患者采用炔雌醇环丙孕酮片单药治疗,2组患者均连续用药3个月,于治疗后第3个月观察患者月经来潮情况,并测定患者的血清睾酮、促卵泡素生成素及促黄体生成素水平。结果:与治疗前比较,治疗后2组患者血清睾酮、促卵泡素生成素及促黄体生成素水平均显著下降,各组内差异有统计学意义(P<0.05);治疗后,治疗组患者血清睾酮、促卵泡素生成素及促黄体生成素水平与对照组的差异无统计学意义(P>0.05);治疗组月经恢复正常患者的比例(94%,62/66)高于对照组(76%,52/68),差异有统计学意义(P<0.05)。结论:采用妇科再造胶囊与炔雌醇环丙孕酮片联合治疗多囊卵巢综合征,可以纠正患者性激素代谢紊乱,有效改善临床症状,具有确切的治疗效果。

OBJECTIVE：To evaluate the efficacy of Gynecological reengineering capsule plus Diane 35 for polycystic ovary syndrome （ PCOS ） .METHODS： 134 gynecological patients with polycystic ovary syndrome patients treated in Wuhan University People’s Hospital were randomly assigned to either control group （n=68） or treatment group（n=66）. The patients in the treatment group were treated with gynecological reengineering capsule combined with Diane -35 and those in the control group with Diane-35 alone for 3 consecutive months .At 3 months , the menstrual onset was followed and serum testosterone , follicle-stimulating hormone and luteinizing hormone levels were measured .RESULTS： The levels of serum testosterone , follicle-stimulating hormone and luteinizing hormone in both groups showed significant reduction as compared with before treatment （ P〈0.05 ）; however , the differences between the two groups were not statistically significant （P〉0.05）;the proportion of patients whose menstruation returned to normal was higher in the treatment group than in the control group [94%（62/66） vs.76%（52/68）, P〈0.05].CONCLUSIONS：Treatment of polycystic ovary syndrome with Diane-35 plus gynecological reengineering capsule resulted in correction of patients ’sex hormone metabolic disorder , improvement of clinical symptoms and proved efficacy .