乳腺叶状肿瘤48例临床病理分析

Clinical and pathological features of 48 cases of breast phyllodes tumor

目的：探讨乳腺叶状肿瘤（phyllodes tumor,PT）的临床病理学特征。方法：对2007年1月~2014年9月泸州医学院附属医院经手术切除的48例乳腺叶状肿瘤患者的临床病理资料进行回顾性研究。结果：48例PT患者均为女性,平均年龄41岁。均以乳腺肿块就诊,肿块直径从1.5~25 cm不等,平均6.7 cm。所有患者均接受手术治疗,其中22例行肿块单纯切除术,14例行肿块扩大切除术,12例行乳房切除术。参照2003版WHO标准将组织学分级分为良性PT 27例,交界性PT 15例,恶性PT 6例。其中30例获随访3~48个月,随访期间肿瘤复发4例。结论：PT是一种较少见的乳腺肿瘤,准确把握PT的临床病理特点,有助于明确诊断。

Objective： To investigate the clinical and pathological features of breast phyllodes tumor.Methods： From January 2007 to September 2014, the clinical and pathological data of 48 cases of phyllodes tumor after surgical removal were retrospectively analyzed. Results： All the patients were women with the average age of 41 years old. The size of tumors ranged from 1.5 cm to 25 cm in diameter, with the average size of6.7 cm. All patients underwent surgical treatments, 22 cases with local mass excision, 14 cases with expanded section resection and 12 cases with total mastectomy. Among the 48 cases of phyllodes tumor, 27 cases were benign, 15 cases were borderline, and 6 cases were malignant. 30 cases were followed-up from 3 months to 48 months, during which 4 cases had recurrence. Conclusion： Breast phyllodes tumor is not common, and mastering the clinical and pathological features is useful to diagnosis this disease.