丝素-纳米麦饭石多孔材料的制备与结构研究

Study on Preparation of Silk Fibroin-Nano Medical Stone Porous Materials and Its Structure

探索了不同粒径范围的麦饭石溶液的制备条件,在再生丝素蛋白自组装形成固态材料的过程中,选择加载粒径小于20 nm的纳米麦饭石制备了丝素-纳米麦饭石共混多孔材料,测试了材料的结构。FT-IR和XRD结果显示:纳米麦饭石对丝素蛋白二级结构没有明显的影响,但可诱导丝素蛋白Silk I结晶结构的形成;经去离子水浸泡后的共混材料显示出明显的麦饭石特征峰。SEM结果表明:麦饭石纳米颗粒能比较稳定地分散并与丝素蛋白共混,孔壁和孔内极少发现麦饭石颗粒析出。

This paper explored preparation conditions of medical stone solution with different particle size ranges,selected nano medical stone with particle size less than 20 nm to prepare silk fibroin-nano medical stone blended porous material,and tested material structure. FT-IR and XRD results show that,nano medical stone has no significance effect on secondary structure of silk fibroin,but can induce formation of silk I crystal structure of silk fibroin; blended material soaked by deionized water shows significant characteristic peak of medical stone. SEM result indicates that nanoparticles of medical stone disperse well and blend with silk fibroin,without obvious precipitation of large particles in the wall of holes or in the holes.