“香连”溶液干膏剂体外抑菌试验研究

Study on Bacteriostasis in Vitro of“Xianglian”Solution Dry Paste

本试验旨在探讨中草药体外抑菌作用,为纯中草药消毒剂的临床使用和扩大临床使用范围提供科学依据。本试验以金黄色葡萄球菌、大肠杆菌、沙门氏菌为模式菌株,以抑菌圈直径、抑菌浓度、细菌生长曲线和抑菌温度曲线为检测指标,研究纯中草药消毒剂"香连"溶液干膏剂的抑菌活性。试验结果显示,对3种模式菌株的抑杀效果由强到弱依次为金黄色葡萄球菌、大肠杆菌、沙门氏菌,MIC分别为7.81、31.25、250mg/mL,所需时间分别为2、2、6h,对金黄色葡萄球菌、沙门氏菌抑杀环境温度为25、37℃。结果表明,"香连"溶液消毒剂不仅可作为环境消毒剂,也可作为饮水消毒剂和细菌性疾病的治疗药物。

The study was aimed to investigate the effect of bacteriostasis in vitro of Chinese herbal medicine,and provide scientific basis for the clinical use of pure Chinese herbal disinfectant and expanding the scope of its clinical use.To study the antibacterial activity of pure Chinese herbal disinfectant＂Xianglian＂solution dry paste,Staphylococcus aureus,Escherichia coli and Salmonellastrains were used as the type strains,the inhibition zone diameter,inhibitory concentration,growth curve of bacteria and bacteriostatic temperature curve were detected in this study.The results showed that the killing effect of 3type strains from strong to weak were Staphylococcus aureus,Escherichia coli,Salmonella;The corresponding MIC were 7.81,31.25 and 250mg/mL,respectively;The corresponding required time were 2,2and 6h,respectively;And the environment temperature of inhibiting and killing Staphylococcus aureus and Salmonella were 25 and 37 ℃,respectively.The research results showed that＂Xianglian＂solution not only could be used as environmental disinfectant,but also could be used as drinking water disinfectant and therapeutic drug in bacterial diseases.