埃博拉出血热的发病机制与病理研究进展

The research progress in the pathogenesis and pathological studies of Ebola hemorrhagic fever

埃博拉出血热（EHF）于1976年在非洲被首次确诊。该病之所以能引起人们的恐慌，原因在于埃博拉出血热是一种可以在人与人之间传播，并且能引起人类严重病变的疾病。目前该病主要集中在非洲地区，其病死率高达35．4％。2014年2月埃博拉出血热在几内亚再一次爆发，并引起世界卫生组织和各国的严密关注。因而总结埃博拉出血热的发病机制和病理变化的最新研究进展具有现实意义。

Ebola hemorrhagic fever was first diagnosed in Africa in 1976. The reason why the disease can cause people to panic is that Ebola hemorrhagic fever is a disease that can spread from person to person and cause severe lesions of human. Now, the disease is mainly concentrated in the Africa area. Its mortality rate as high as 35.4%. In February 2014 ,the outbreak of Ebola hemorrhagic fever occuned again in Guinea. It caused the close attention of world health or ganization （WHO） and many countries. In order to deal with Ebola hemorrhagic fever, the latest research progress in the pathogenesis and pathological changes of this disease are summarized.