2009-2013年南京地区自愿无偿献血者梅毒感染的检测分析

Detection of syphilis infection among volunteer blood donors from 2009 to 2013 in Nanjing,China

目的了解南京地区无偿献血人群的梅毒流行病学特征,加强临床用血质量控制,为制定经血液梅毒传播防治策略提供依据。方法双抗原夹心酶联免疫法,按照试剂盒使用说明书操作,初检结果有反应性者进行双孔复试。结果 2009-2013年共检测南京地区献血者血液样本363 331人份,其中梅毒螺旋体检测阳性1 371例,阳性率为0.38%。结论加大无偿献血相关知识宣传,特别是高危人群的健康教育,做好献血前的征询工作。为保证临床用血安全,应从低危人群中招募献血者,发展固定献血者队伍,减少血液报废。

Objectives To understand the epidemiological characteristics of syphilis infection in blood donors in Nanjing,to strengthen quality control of clinical use and to provide scientific evidence for preventative strategy and measures.Methods Double antibody sandwich method of ELISA was employed,according to the kit instructions.Positive test results were examined using second round of double test.Results 363,331 blood samples were collected from 2009 to 2013,of which,1,371 samples were detected to be positive.The average rate of syphilis infection was 0.38%.Conclusion It is necessary to raise awareness on blood donation and educate high-risk populations to conduct consultation before blood donation.To ensure blood safety,it is important to recruit low-risk blood donors and develop a permanent team of volunteer blood donors in order to reduce blood waste.