当飞利肝宁胶囊防治抗结核药物性肝损伤临床分析

目的:探讨当飞利肝宁胶囊防治抗结核药物性肝损伤的保肝作用。方法:将121例初治结核病患者随机分为两组,实验组61例,对照组60例。实验组加用当飞利肝宁胶囊,对照组未加用任何保肝药。每月复查肝功能,若出现轻度肝功损伤则加用当飞利肝宁胶囊保肝治疗。结果:肝损伤发生率对照组显著高于实验组(P<0.05),差异有统计学意义;轻度肝损害者肝功能治愈率达80%,有效率100%。结论:当飞利肝宁胶囊能有效预防和治疗抗结核药物所致肝损伤。

Objective：To discuss the hepatoprotective effect of Dangfei Liganning capsule in liver injury induced by anti-tuberculosis drugs.Methods： 121 patients of initial treatment tuberculosis were randomly devided into two groups, the treatment group （n=61） and the control group （n= 60）.meanwhile the treatment group was given Dangfei Liganning capsule,but the control group without any hepatoproteetive drug.Monitored liver function every month, and given Dangfei Liganning capsule when slight drug-induced liver injury. Results：The incidence of liver injury were significantly higher than those in the experimental group, the difference was statistically significant （P〈0.05）; Liver damage control group of patients with mild liver damage liver function cure rate of 80%, the effective rate was 100%.Conclusion ：Dangfei Liganning capsule effectively prevent and cure liver injury induced by anti-tuberculosis drugs.