宫颈环形电圈切除术治疗宫颈上皮内瘤变的临床效果观察

Clinical effect observation of cervical loop electrosurgical excision proce-dure treating cervical intraepithelial neoplasia

目的探讨宫颈环形电圈切除术（LEEP术）治疗宫颈上皮内瘤变（CIN）的临床效果。方法选取2009年6月~2014年6月本院收治的CINⅡ、Ⅲ期患者100例,其中,44例行子宫颈冷刀锥切术（CKC组）,56例行宫颈LEEP术（LEEP组）,观察两组的手术、术后恢复情况,术后并发症、病变复发情况。结果两组患者均顺利完成手术,术中切割宫颈组织时患者有下腹胀痛和阴道局部发热感,患者多可耐受;LEEP组的术中出血量明显少于CKC组（P〈0.05）、阴道排液时间与宫颈创面修复时间较CKC组明显缩短（P〈0.05）。两组的手术时间、住院时间比较,差异无统计学意义（P〉0.05）;LEEP组的脱痂期出血及感染发生率明显低于CKC组（P〈0.05）,两组的子宫颈狭窄发生率、复发率比较,差异无统计学意义（P〉0.05）;观察组的术后并发症发生率低于CKC组（P〈0.05）。结论 LEEP术治疗CIN能够缩短手术时间,减少术中出血量,降低术中缝合止血率,并发症少,受术者易于接受。

Objective To investigate the clinical effect of cervical loop electrosurgical excision procedure（LEEP） treating cervical intraepithelial neoplasia（CIN）. Methods 100 patients with CIN of stage Ⅱ and Ⅲ treated in our hospital from June 2009 to June 2014 were selected,and among them,44 cases were given cervical cold knife conization（the CKC group）,56 cases were given LEEP operation（the LEEP group）.The operation and postoperative recovery condition,postoperative complication and recurrence of lesion in the two groups were observed. Results Patients of the two groups were successfully completed surgery,patients had lower abdominal pain and vaginal local fever when cutting the cervical tissue during operation,more patients could tolerate.The intraoperative bleeding amount in the LEEP group were obviously fewer than those in the CKC group（P〈0.05）,the time of vaginal discharge and cervical wound healing time in the LEEP group was significantly shorter than the CKC group respectively（P〈0.05）. Operation time,hospitalization time of the two groups have no statistical difference（P〈0.05）;the incidence rate of decrustation period haemorrhage and infection rate in the LEEP group was obviously lower than that in the CKC group respectively（P〈0.05）,and there was no satistical difference of the incidence rate of stenosis of cervix,the reoccurrence rate in the two groups（P〈0.05）;the incidence rate of postoperative complication in the LEEP group was lower than that in the CKC group（P〈0.05）. Conclusion LEEP operation treating CIN can shorten operation time,reduce bleeding amount during operation,reduce the operation suture hemostasis rate,and fewer complication,and it is easy to be accepted the subject.