干细胞治疗疾病及安全性的研究进展

Advance in application and safety of stem cell therapy

近年来,干细胞治疗疾病是一个新的研究热点,在治疗心血管疾病、糖尿病、骨髓及软骨损伤、神经系统疾病以及恶性肿瘤等方面有广泛的应用。它是通过干细胞移植并迁移到损伤部位修复受损的细胞或组织的一种疗法,主要应用在因细胞或组织损伤引起的疾病,而且自体移植干细胞避免了免疫排斥和伦理道德问题。利用干细胞治疗这些疾病有一定的发展前景,为很多难以治愈的疾病提供了新的治疗途径和技术方法。然而,随着干细胞治疗疾病这项新技术的发展,安全性问题也引起了广泛的关注。因此,在干细胞应用到临床前,进行严格的安全性评价是很有必要的,这样才能保证干细胞治疗安全、稳定的造福于人类。

In recent years,stem cell therapy has become a new research hotspot and has been widely used in the treatment of cardiovascular disease,diabetes,bone and cartilage damage,neurological diseases,cancer,and so on. The stem cell therapy can repair damaged cell or tissue caused by related diseases through cell transplantation and cell migration. Moreover,the application of autologous stem cell transplantation effectively avoids the challenge of immune rejection and moral problems. In general,stem cell therapy has a good development prospect,and provides a new therapeutic approach and technique for many intractable diseases. However with the development of stem cell therapy,safety issues have attracted more and more attention. In order to ensure the safety of stem cells and the health of human,it is necessary to conduct a rigorous safety assessment before clinical application of stem cells.