献血前后代谢综合征相关血液指标变化

Changes of metabolic syndrome related indexes before and after blood donation in blood donors

目的分析代谢综合征（MS）的高危献血者献血前后的血压及相关生化指标来探讨献血对预防MS的意义。方法研究对象为男性或绝经后女性共102例,年龄45～55岁,收缩压110～140 mm Hg,舒张压75～90 mm Hg,体质量指数大于24kg/m^2,献血前测定血压、心率、铁储量、血糖、血脂等指标与献血42d后再测定相同指标进行比较。结果血压、铁储量、血糖、低密度脂蛋白/高密度脂蛋白（LDL/HDL）与献血前比较差异有统计学意义（P〈0.05）。结论献血前后MS相关血液指标存在变化,献血对于MS高危者预防MS具有一定意义。

Objective To investigate the significance of blood donation in preventing metabolic syndrome（MS）by analyzing the changes of the blood pressure and the related biochemical indexes before and after blood donation in the blood donors with high risk of MS.Methods The blood specimens of 102 blood donors,aged 45-55 years old with the systolic blood pressure of 110-140 mmHg and the diastolic blood pressure of 75-90 mmHg,the body mass index 〉24kg/m^2,were selected as the subjects.The blood pressure,heart rate,iron reserves,blood glucose,blood lipids,and the other indicators were determined before blood donation.All the above indicators were tested again on 42 dafter blood donation.Results The blood pressure,iron reserves,blood glucose and LDL/HDL ratio after donation showed significant changes compared with before blood donation（P〈0.05）.Conclusion The changes of the MS related blood indexes exist before and after blood donation,blood donation has a certain significance for preventing MS in the blood donors with high risk of MS.