血清淀粉酶和脂肪酶联合检测在急性胰腺炎诊断中的应用

Application of combined detection of serum amylase and lipase in diagnosis of acute pancreatitis

目的分析血清淀粉酶(AMY)和脂肪酶(LPS)检测方式在急性胰腺炎诊断中的价值。方法选取2012年1月至2014年2月收治的100例急性胰腺炎患者和100例健康体检者行AMY与LPS检测,分析检测结果及其灵敏度、准确度、特异度。结果重度急性胰腺炎组与轻度急性胰腺炎组患者的AMY、LPS水平高于对照组,差异有统计学意义(P<0.05);重度急性胰腺炎组AMY、LPS水平比轻度急性胰腺炎组高,差异有统计学意义(P<0.05);AMY、LPS联合检测的准确度、特异度、灵敏度高于两者单独检测结果。结论 AMY联合LPS检测可以为急性胰腺炎提供重要的诊断依据。

Objective To analyze the value of the detection mode of serum amylase（AMY）and lipase（LPS）in the diagnosis of acute pancreatitis.Methods 100 patients with acute pancreatitis and 100 individuals of healthy physical examination in our hospital from January 2012 to February 2014 were selected and detected serum AMY and LPS.The detection results,sensitivity,accuracy and specificity were analyzed.Results The serum AMY and LPS levels in the severe acute pancreatitis group and the mild acute pancreatitis group were higher than that in the control group,the difference was statistically significant（P〈0.05）;the serum AMY and LPS levels in the severe acute pancreatitis group were higher than those in the mild acute pancreatitis group,the difference was statistically significant（P〈0.05）;the accuracy,specificity and sensitivity of the combined detection of AMY and LPS was higher than that of the single index detection.Conclusion The joint detection of AMY and LPS can provide the important diagnostic basis for acute pancreatitis.