改良B-Lynch缝合联合米索前列腺醇治疗剖宫产后出血疗效观察

Combined therapy of modified B-Lynch suture and Misoprostol in treatment of postpartum hemorrhage after caesarean section

目的探讨改良B-Lynch缝合联合米索前列腺醇在治疗剖宫产产后出血中的应用。方法选择66例剖宫产产后出血患者作为研究对象,按照随机数字表法平均分为对照组及治疗组,均接受改良B-Lynch缝合手术治疗,治疗组则在此基础上联用米索前列腺醇600μg口服治疗。观察并比较两组患者的出血量、临床疗效、手术时间以及术后血性恶露持续时间等指标。结果治疗组治疗有效率为87.88%,显著高于对照组的75.76%(x^2=4.58,P<0.05)。治疗组术后2h及24h出血量均显著低于对照组(t值分别为3.24、6.55,均P<0.05),治疗组术后血性恶露持续时间也显著短于对照组(t=5.07,P<0.05)。结论改良B-Lynch缝合联合米索前列腺醇是治疗剖宫产产后出血的可靠而有效的手段,值得临床推广应用。

Objective To explore the clinical application of combined therapy of modified B-Lynch suture and Misoprostol in treatment of postpartum hemorrhage after caesarean section. Methods A total of 66 patients with postpartum hemorrhage after caesarean section were selected and divided into control group and treatment group evenly and randomly. All of the patients received B-Lynch suture, and the treatment group received additional treatment of oral administration of Misoprostol. Clinical treatment efficacy, hemorrhage amount, surgery duration and bloody lochia duration were observed and compared between two groups. Results Clinical efficacy of the treatment group （87.88%） was significantly higher than the control group （75.76%） （χ^2 =4.58, P 〈0.05）. Hemorrhage amount 2h and 24h after surgery was significantly less in the treatment group than in the control group （t value was 3.24 and 6.55, respectively, both P 〈 0.05 ）, and bloody lochia duration was also significantly shorter in the treatment group （ t = 5.07 ,P 〈 0.05 ）. Conclusion Combined therapy of B- Lynch suture and Misoprostol shows reliable effects in treatment of postpartum hemorrhage after caesarean section. So it is worthy of spread in clinics.