玫瑰花中苯丙素和苯乙醇类化学成分的研究

Phenylpropanoids and phenylethanoids from the Rosa rugosa

采用硅胶色谱、高效液相制备色谱对产自云南呈贡的玫瑰花进行分离、纯化化学成分,通过UV、IR、MS、NMR等波谱方法进行结构鉴定.分离得到了8个苯丙素和苯乙醇类已知化合物,分别鉴定为Ferulic acid(1),ω-Hydroxypropioguaiacone(2),(E)-Ferulaldehyde(3),1-Propanone-2-hydroxy-1-(3-methoxy-4-hydroxyphenyl)(4),Evofolin(5),2-(3'-O-β-D-Glucopyranosyl-4'-hydroxyphenyl)-ethanol(6),2-(3-Hydroxy-4-O-D-β-glucopyranosyl)phenyl-ethanol(7),2(3,4-Dihydroxy-phenyl)-ethanol(8).这些化合物均为首次从呈贡玫瑰花中分离得到.

The research aimed to study the chemical constituents from Rosa rugosa in Chenggong of Yunnan province. The constituents were isolated and purified by the silica column chromatography and HPLC. Their structures were elucidated by spectroscopy. Eight phenylpropanoids and phenylethanoids were obtained and identified as follows： Ferulic acid（ 1）,ω-Hydroxypropioguaiacone（ 2）,（ E）-Ferulaldehyde（ 3）,1-Propanone-2-hydroxy-1-（ 3-methoxy-4-hydroxyphenyl）（ 4）,Evofolin（ 5）,2-（ 3＇-O-β-D-Glucopyranosyl-4＇-hydroxyphenyl）-ethanol（ 6）,2-（ 3-Hydroxy-4-O-D-β-glucopyranosyl） phenyl-ethanol（ 7）,and 2（ 3,4-Dihydroxy-phenyl）-ethanol（ 8）. These compounds are obtained from this plant for the first time.